Introduction Solid tumors present an ongoing challenge in immunotherapy, owing largely to the complexities of the tumor microenvironment (TME). While immunotherapies have drastically improved outcomes for many patients with these malignancies, not all solid tumors are equal; even best-in-class immunotherapies fail to induce durable responses in the majority of patients with solid tumors.  But why … Continue reading Firing Up the Cold Tumor: A Major Obstacle in Cancer Therapy